Which of the following is not a component of the reticuloendothelial cell system?

Study for the Certified Histocompatibility Specialist Test. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Neutrophils are not considered a component of the reticuloendothelial cell system, which is primarily made up of macrophages and other specialized phagocytic cells that are involved in the immune response. This system includes various types of cells that have in common their origin from monocytes in the bone marrow and their function in phagocytosis, antigen presentation, and the secretion of cytokines.

Microglial cells, found in the central nervous system, act as the primary immune cells in that region and are derived from yolk sac progenitors, thus categorizing them within the reticuloendothelial system. Kupffer cells, located in the liver, are specialized macrophages that help filter bacteria and dead cells from the bloodstream, also fitting into this system's framework. Langerhans cells, a type of dendritic cell found in the skin, share similar functions in immune surveillance and antigen presentation, further aligning them with the reticuloendothelial cell system.

In summary, neutrophils are primarily associated with acute inflammatory responses and do not play a central role in the reticuloendothelial system, which is more focused on chronic immune responses and surveillance.

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