What is the probable haplotype assignment for sibling #2 based on the family data?

To determine the probable haplotype assignment for sibling #2 based on family data, it is important to analyze the inheritance of HLA (Human Leukocyte Antigen) haplotypes from the parents. HLA is inherited in a Mendelian fashion, where each sibling receives one haplotype from each parent.

In the context of the question, the assignment of A11, B60, DR13 as the probable haplotype for sibling #2 suggests that sibling #2 has inherited these specific alleles, consistent with the patterns observed in sibling relationships. A haplotype represents a specific combination of alleles at the HLA loci that are inherited together from one parent.

When looking at family data, compatibility of HLA haplotypes is crucial for processes such as organ transplantation or identifying potential matches for bone marrow donations. If sibling #1 has a known haplotype, sibling #2 must either have one of the same haplotypes or a combination that reflects a different allelic variant from the parents. The selection of this particular combination indicates that it aligns with the inheritance observed in the family, while also taking into account the need for diversity in immune response that may benefit the siblings.

Thus, the haplotype assignment of