If the frequencies of alleles A and B are 0.2 and 0.6, respectively, what is the probability of an AA child in a mating of AB x AB parents?

Study for the Certified Histocompatibility Specialist Test. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

To determine the probability of having an AA child from a mating of AB x AB parents, we can use a Punnett square to visualize the potential genetic combinations. Each parent contributes one of their alleles to the offspring.

In this scenario, each AB parent can pass on either the A allele or the B allele, leading to the following possible combinations for the offspring:

  1. AA (A from the first parent and A from the second parent)
  2. AB (A from the first parent and B from the second parent)
  3. BA (B from the first parent and A from the second parent)
  4. BB (B from both parents)

We can summarize these outcomes based on the allele frequencies:

  • The probability of an offspring being AA is the product of the probabilities of each parent contributing an A allele. Each AB parent has a 0.2 (or 20%) chance of passing on an A allele. Thus, the probability for AA offspring is calculated as:

[ P(AA) = P(A \text{ from parent 1}) \times P(A \text{ from parent 2}) = 0.2 \times 0.2 = 0.04 ]

However, in this case,

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